August 9, 2016

Brain metastases

Brain metastases are a common complication of cancer, with a dismal prognosis. There is a limited understanding of the oncogenic alterations harbored by brain metastases and whether these are shared with their primary tumors or other metastatic sites. In collaboration the Broad Institute, and with many institutions nationally and internationally, we are currently comprehensively characterizing the genomics of brain metastases to understand the molecular pathways that drive these tumors. We are also building animal models to further study possible genetic drivers.